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Clinical vs Street Ketamine

ClubDrugs.org Health Desk Published 3 min read
Clinical vs Street Ketamine
Photo: Gruppe 2 ap0813 · CC BY-SA 4.0 · Wikimedia Commons

It's important to understand that no IV product is FDA approved for depression.

Insurance coverage for ketamine therapy depends on several factors. Insurance coverage is more common for Spravato than for off-label IV ketamine.

When used for depression, the process looks like this:

  1. Severe depression was diagnosed, usually by a psychiatrist, based on DSM criteria. This was considered treatment-resistant, meaning it had not responded to other medication or therapy options.
  2. Spravato is administered in a specific clinic setting.
  3. REMS: Patients are monitored for at least 2 hours after administration.

In terms of risks, side effects of ketamine include dizziness, sedation, nausea, dysarthria, and dream-like or floating sensations. The risks of recreational ketamine use are significant; using a needle to administer ketamine carries significant risks, as do its concurrent use of opioids, alcohol or benzodiazepines, too.

Still, there is no equivalent to this careful monitoring or patient interaction in the street use of ketamine. The medical process exists for a reason in therapy.

If you or someone you know is considering ketamine, the first step should be to consult a licensed mental-health professional. Ask about the specific treatment option, such as Spravato or IV ketamine. Do not seek ketamine based on one's own diagnosis of depression: research indicates that Spravato is not a cure-all, but rather a targeted treatment for specific, severe symptoms. If ethical or medical concerns arise, stop ketamine use and contact a doctor immediately.

This guide is general health information, not medical or legal advice. Talk to a doctor or pharmacist about your situation. In an emergency call 911.

If someone is in danger right now

Unresponsive, breathing slowly or noisily, overheating, having a seizure or chest pain: do not wait for it to pass.