MDMA and SSRI Risks
If you take an SSRI antidepressant and are considering using MDMA, know that the two drugs interact at the serotonin system. The main risk is that SSRIs can blunt MDMA’s effects, but that…
3 min readDrug Interaction Guides
The combinations emergency doctors see most often: party drugs with alcohol, with antidepressants and with each other.
Cocaethylene: Cocaine Plus Alcohol
Dangerous heart risks come from mixing cocaine and alcohol; in the liver, ethanol and cocaine form cocaethylene, a metabolite that poses special risks to the heart.
3 min read
Mixing Alcohol and Depressants
Mixing alcohol with GHB (specifically gamma-hydroxybutyrate) or ketamine is an extraordinarily dangerous combination, causing extreme sedation, respiratory depression, and a high risk of…
3 min readIf someone is in danger right now
Unresponsive, breathing slowly or noisily, overheating, having a seizure or chest pain: do not wait for it to pass.
- Call 911
Say what was taken if you know. Many states protect the caller: see Good Samaritan laws.
- Keep the airway open
Roll the person onto their side and stay with them. Why mixing depressants is so dangerous.
- Give naloxone if you have it
It reverses opioid overdoses and is sold without a prescription. Where to get Narcan.
- Poison Control 1-800-222-1222
- SAMHSA Helpline 1-800-662-4357, free, 24/7